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Denmark propose the use of Blockchain Platforms for fighting against corruption on government and institutional levels

The Ministry of Foreign Affairs of Denmark published a report explaining the use of IT technologies and services including blockchain, e-governance, big data, and crowdsourcing to fight administrative, or day-to-day, corruption as well as political corruption.

Presented during the International Anti-Corruption Conference, or IACC, the report emphasizes the use of blockchain as a technology that will build a more transparent governance and transaction system, further adding that it will also give individuals greater rights over their own data.

According to the report, blockchain can be used as a potential anti-corruption tool as it has the ability to store records immutably and transparently. A public database such as blockchain also provides every individual equal access to the data stored in the ledger, thus allowing individuals to claim their rights over aid, land and money without depending on any middlemen.

The report further says that blockchain “reduces or eliminates the need for institutions” such as banks, land registries, accountants, registry of births and deaths, and vehicle registration whose main job is to validate transactions.

The technology would help entities efficiently and securely share resources with people without formal identities or bank accounts, the report adds.

The public sector may also use blockchain to secure records and certificates from any alterations and use blockchain’s ability to trace all activities to reduce the chances for corruption.

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Social Networks – secure, decentralized – have you deleted Facebook, Twitter and Instagram yet?

 These token-enabled communication platforms may help you take the leap.

  • Minds: A censorship-resistant social network that integrates ERC-20 tokens

  • Peepeth: Like Twitter, but decentralized and token-integrated.

  • Akasha: A decentralized social network built on Ethereum.

  • Numa: A no-frills, distributed social media platform.

  • Indorse: Coding assessment platform and online code review for programmers, by programmers.

  • Cent: The income-generating social network, enabling anyone to earn money by sharing their wisdom and creativity.

  • Livepeer: Open source video infrastructure services for live video broadcasting.

  • Refereum: Earn rewards for playing games, watching streams, and sharing gaming content with your friends.

  • VouchForMe: A distributed insurance platform based on social proof built on Ethereum.

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MyEtherWallet to Offer ‘.Crypto’ Blockchain Domains to 1 Million Users

Unlike with traditional domain registration, custody of the domain is tied to the specific wallet and is not controlled by any centralized entity.

The .crypto domain is based on Unstoppable Domains’ smart contracts on Ethereum, which are responsible for assigning the domains and looking up the addresses.

It is separate from the Ethereum Name Service (ENS), which assigns .eth domains, but the functionality is similar. Unstoppable Domains can tie the .crypto domain to an Ethereum wallet, making it possible to send money to human-readable addresses.

Building an uncensorable web

The company is also pushing the .crypto domain as an uncensorable alternative to existing web addresses.

Since it falls outside of the traditional domain name infrastructure, normal browsers cannot open .crypto websites. As reported by Cointelegraph in March, the Opera browser entered into a partnership with Unstoppable Domains to accept blockchain-based domains. 

Opera nevertheless only holds 2.2% of the global market share. For Chrome users, Unstoppable Domains released a browser extension.

The company stresses that blockchain domains are not going to make the web uncensorable by themselves, but they help users bypass restrictions when publishing content.
— Citește pe cointelegraph.com/news/myetherwallet-to-offer-crypto-blockchain-domains-to-1-million-users

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Charities Are Turning to Bitcoin Amid the Global Fight Against Coronavirus

In the war against the novel coronavirus, cryptocurrencies are emerging as a much-needed tool for charity and fundraising projects. Already there are a number of large nonprofits accepting Bitcoin donations. Plus, some blockchain and crypto firms are contributing medical supplies to hospitals in an attempt to curb the virus, while others are setting up fundraisers and charities that are aimed at helping its victims.
As a number of nonprofits continue to accept cryptocurrency donations, they are starting to realize that crypto transactions significantly reduce costs in terms of fees. Here are a number of charities and fundraisers that accept donations in crypto.
Red Cross
The rate of coronavirus infections in Italy is astonishingly high. For this reason, the Italian Red Cross moved to accept Bitcoin (BTC) and other crypto donations on March 12 with the goal of using the proceeds from the campaign to set up second-level advanced medical posts. The medical posts would be used to pre-triage coronavirus patients.
The project turned out to be such a success such that its fundraising goal of $10,710 was achieved by the third day of the campaign. Since then, the charitable organization has moved to raise even more funds through Bitcoin and other crypto donations with the goal of $26,000. The funds from the second round of funding are set to be used to buy emergency equipment. So far, the organization has achieved around 85% of its goal.
The Water Project
Apart from social distancing, one of the frequent calls by hygiene experts has been to wash hands. Without a doubt, hand washing is one of the crucial ways of fighting the spread of the coronavirus. Charitable organizations such as The Water Project have been at work installing and repairing water points all over impoverished regions in Africa. 
They have also been teaching communities how to wash hands and how to keep their water sources free from germs and other pathogens, as well as how to begin and maintain other good health practices. With coronavirus spreading through various countries in Africa, charitable organizations like The Water Project are crucial for the containment of the virus. 
For the first time, the organization has launched a fundraising project called WaSH — an acronym for water sanitation and hygiene — with the aim of raising funds to provide clean water and hygiene. Aside from standard methods of donation, the water project also accepts crypto donations in Bitcoin, Bitcoin Cash (BCH), Ether (ETH) and Litecoin (LTC).
— Citește pe cointelegraph.com/news/charities-are-turning-to-bitcoin-amid-the-global-fight-against-coronavirus

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Scientific sources: China Treating Coronavirus COVID-19 with Intravenous Vitamin C

 

Scientific source 1:

Source: https://stm.sciencemag.org/content/12/532/eaay8707

A vitamin boost for immunotherapy

Despite some controversy over the years, it is gradually becoming clear that vitamin C has some anticancer effects, albeit only when given intravenously and at sufficiently high doses. However, earlier studies evaluating the anticancer effects of vitamin C have used immunodeficient mice and therefore only examined its direct effects on tumors. By studying immunocompetent mouse models of cancer, Magri et al. determined that the vitamin’s effects were much stronger in the presence of an intact immune system and that it cooperated with checkpoint immunotherapy. These findings suggest a promising approach to combination treatment, which now needs to be tested in patients.

Abstract

Vitamin C (VitC) is known to directly impair cancer cell growth in preclinical models, but there is little clinical evidence on its antitumoral efficacy. In addition, whether and how VitC modulates anticancer immune responses is mostly unknown. Here, we show that a fully competent immune system is required to maximize the antiproliferative effect of VitC in breast, colorectal, melanoma, and pancreatic murine tumors. High-dose VitC modulates infiltration of the tumor microenvironment by cells of the immune system and delays cancer growth in a T cell–dependent manner. VitC not only enhances the cytotoxic activity of adoptively transferred CD8 T cells but also cooperates with immune checkpoint therapy (ICT) in several cancer types. Combination of VitC and ICT can be curative in models of mismatch repair–deficient tumors with high mutational burden. This work provides a rationale for clinical trials combining ICT with high doses of VitC.

 

 


Scientific Source 2:

Source: https://journal.chestnet.org/article/S0012-3692(16)62564-3/fulltext

Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock

Background

The global burden of sepsis is estimated as 15 to 19 million cases annually, with a mortality rate approaching 60% in low-income countries.

Methods

In this retrospective before-after clinical study, we compared the outcome and clinical course of consecutive septic patients treated with intravenous vitamin C, hydrocortisone, and thiamine during a 7-month period (treatment group) with a control group treated in our ICU during the preceding 7 months. The primary outcome was hospital survival. A propensity score was generated to adjust the primary outcome.

Results

There were 47 patients in both treatment and control groups, with no significant differences in baseline characteristics between the two groups. The hospital mortality was 8.5% (4 of 47) in the treatment group compared with 40.4% (19 of 47) in the control group (P < .001). The propensity adjusted odds of mortality in the patients treated with the vitamin C protocol was 0.13 (95% CI, 0.04-0.48; P = .002). The Sepsis-Related Organ Failure Assessment score decreased in all patients in the treatment group, with none developing progressive organ failure. All patients in the treatment group were weaned off vasopressors, a mean of 18.3 ± 9.8 h after starting treatment with the vitamin C protocol. The mean duration of vasopressor use was 54.9 ± 28.4 h in the control group (P < .001).

Conclusions

Our results suggest that the early use of intravenous vitamin C, together with corticosteroids and thiamine, are effective in preventing progressive organ dysfunction, including acute kidney injury, and in reducing the mortality of patients with severe sepsis and septic shock. Additional studies are required to confirm these preliminary findings.

 


Why China Treating Coronavirus COVID-19 with Intravenous Vitamin C ?

Intravenous vitamin C is already being employed in China against COVID-19 coronavirus. I am receiving regular updates because I am part of the Medical and Scientific Advisory Board to the International Intravenous Vitamin C China Epidemic Medical Support Team. Its director is Richard Z. Cheng, MD, PhD; associate director is Hong Zhang, PhD.

Among other team members are Qi Chen, PhD (Associate Professor, Kansas University Medical School); Jeanne Drisko, MD (Professor, University of Kansas Medical School);

Thomas E. Levy, MD, JD; and Atsuo Yanagisawa, MD, PhD. (Professor, Kyorin University, Tokyo). To read the treatment protocol information in English: click this (Protocol in Chinese is here).

Direct report from China

OMNS Chinese edition editor Dr. Richard Cheng is reporting from China about the first approved study of 12,000 to 24,000 mg/day of vitamin C by IV. The doctor also specifically calls for immediate use of vitamin C for prevention of coronavirus (COVID-19). See this.

A second clinical trial of intravenous vitamin C was announced in China on Feb. 13th. In this second study, says Dr. Cheng,

“They plan to give 6,000 mg/day and 12,000 mg/day per day for moderate and severe cases. We are also communicating with other hospitals about starting more intravenous vitamin C clinical studies. We would like to see oral vitamin C included in these studies, as the oral forms can be applied to more patients and at home.” Additional information here.

And on Feb 21, 2020, announcement has been made of a third research trial now approved for intravenous vitamin C for COVID-19.

Dr. Cheng, who is a US board-certified specialist in anti-aging medicine, adds:

“Vitamin C is very promising for prevention, and especially important to treat dying patients when there is no better treatment. Over 2,000 people have died of the COIV-19 outbreak and yet I have not seen or heard large dose intravenous vitamin C being used in any of the cases. The current sole focus on vaccine and specific antiviral drugs for epidemics is misplaced.”

He adds that:

“Early and sufficiently large doses of intravenous vitamin C are critical. Vitamin C is not only a prototypical antioxidant, but also involved in virus killing and prevention of viral replication. The significance of large dose intravenous vitamin C is not just at antiviral level. It is acute respiratory distress syndrome (ARDS) that kills most people from coronaviral pandemics (SARS, MERS and now NCP). ARDS is a common final pathway leading to death.

“We therefore call for a worldwide discussion and debate on this topic.”

Source: 

https://www.globalresearch.ca/three-intravenous-vitamin-c-research-studies-approved-treating-covid-19/5705405

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Shanghai Government Officially Recommends Vitamin C for COVID-19

Guvernul chinez a anunțat recomandarea oficială ca COVID-19 să fie tratat cu cantități mari de vitamina C. intravenoasă !
Recomandările de dozare variază în funcție de severitatea bolii, de la 50 la 200 de miligrame pe kilogram greutate corporală pe zi la aprox. 200 mg / kg / zi.
Aceste doze sunt de aproximativ 4.000 la 16.000 mg pentru un adult, administrate prin IV. Această metodă specifică de administrare este importantă, spune expertul în terapie intravenoasă, Atsuo Yanagisawa, MD, PhD, deoarece efectul vitaminei C este de cel puțin zece ori mai puternic de IV decât dacă este administrat oral. Dr. Yanagisawa este președintele Colegiului japonez de terapie intravenoasă din Tokyo. El spune, “Vitamina C intravenoasă este un antiviral sigur, eficient și cu spectru larg.”
Dr. Cheng și Dr. Yanagisawa recomandă amândoi vitamina C orală pentru prevenirea infecției cu COVID-19 !

(OMNS Mar 3, 2020) The government of Shanghai, China has announced its official recommendation that COVID-19 should be treated with high amounts of intravenous vitamin C. (1) Dosage recommendations vary with severity of illness, from 50 to 200 milligrams per kilogram body weight per day to as much as 200 mg/kg/day.

These dosages are approximately 4,000 to 16,000 mg for an adult, administered by IV. This specific method of administration is important, says intravenous therapy expert Atsuo Yanagisawa, MD, PhD, because vitamin C’s effect is at least ten times more powerful by IV than if taken orally. Dr. Yanagisawa is president of the Tokyo-based Japanese College of Intravenous Therapy. He says, “Intravenous vitamin C is a safe, effective, and broad-spectrum antiviral.”

Richard Z. Cheng, MD, PhD, a Chinese-American specialist physician, has been working closely with medical and governmental authorities throughout China. He has been instrumental in facilitating at least three Chinese clinical IV vitamin C studies now underway. Dr. Cheng is presently in Shanghai continuing his efforts to encourage still more Chinese hospitals to implement vitamin C therapy incorporating high oral doses as well as C by IV.

Dr. Cheng and Dr. Yanagisawa both recommend oral vitamin C for prevention of COVID-19 infection.

An official statement from Xi’an Jiaotong University Second Hospital (2) reads:

“On the afternoon of February 20, 2020, another 4 patients with severe new coronaviral pneumonia recovered from the C10 West Ward of Tongji Hospital. In the past 8 patients have been discharged from hospital. . . [H]igh-dose vitamin C achieved good results in clinical applications. We believe that for patients with severe neonatal pneumonia and critically ill patients, vitamin C treatment should be initiated as soon as possible after admission. . .[E]arly application of large doses of vitamin C can have a strong antioxidant effect, reduce inflammatory responses, and improve endothelial function. . . Numerous studies have shown that the dose of vitamin C has a lot to do with the effect of treatment. . . [H]gh-dose vitamin C can not only improve antiviral levels, but more importantly, can prevent and treat acute lung injury (ALI) and acute respiratory distress (ARDS).” source: http://orthomolecular.org/resources/omns/v16n16.shtml

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Mortality rate comparison Influenza US season 2017-2018 vs Novel Coronavirus (SARS-nCoV-2-2019)

US Center for Disease Control
Influenza-associated disease outcomes
AGEMortality rate %
0-4 yrs0,0006
5-17 yrs0,001
18-49 yrs0,002
50-64 yrs0,0106
65+ yrs0,1001
Average0,02286
China CCDC, February 17 2020
COVID-19 Fatality Rate by AGE
AGEMortality rate %
0-9 yrs0
10-19 years0,2
20-29 years0,2
30-39 years0,2
40-49 years0,4
50-59 years1,3
60-69 years3,6
70-79 years8
80+ years14,8
Average3,188888889
Influenza/nCoV average mortality factor139 times
Data sources: 
https://www.cdc.gov/flu/about/burden/2017-2018.htm
https://www.worldometers.info/coronavirus/coronavirus-age-sex-demographics/

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Expert opinions on New Coronavirus SARS nCoV 2019

The director general of the WHO has recently spoken of a narrowing of the window of opportunity to control the current epidemic. The tipping point – after which our ability to prevent a global pandemic ends – seems a lot closer after the past 24 hours

Prof. Paul Hunter

Professor of Health Protection
University of East Anglia
Feb. 23, 2020


The number of reports from multiple different countries in the past 36 hours showing what is most likely community human to human spread of SARS-CoV-2 confirms fears that the virus is on its way to causing a pandemic

Once the virus establishes an endemic foothold in the human population; it will become difficult if not impossible to eradicate, like other betacoronaviruses (beta-CoV) that infect humans causing seasonal outbreaks of respiratory illness, albeit of lower severity.”

Prof. Dr. Benhur Lee, MD

Professor of Microbiology
Icahn School of Medicine at Mount Sinai (ISMMS)
Feb. 21, 2020


I think it is likely we will see a global pandemic. If a pandemic happens, 40% to 70% of people world-wide are likely to be infected in the coming year. What proportion is asymptomatic, I can’t give a good number

Why do I think a pandemic is likely? The infection is in many parts of China and many countries in the world, with meaningful numbers of secondary transmissions. The scale is much larger than SARS for example (where the US had many introductions and no known onward transmission)

Why do I think 40-70% infected? Simple math models with oversimple assumptions would predict far more than that given the R0 estimates in the 2-3 range (80-90%). Making more realistic assumptions about mixing, perhaps a little help from seasonality, brings the numbers down.

Pandemic flu in 1968 was estimated to _symptomatically_ infect 40% of the population, and in 1918 30%. Those likely had R0 less than COVID-19. Below is from https://stacks.cdc.gov/view/cdc/11425

Prof. Marc Lipsitch

Prof. of Epidemiology, Harvard School of Public Health
Head, Harvard Ctr. Communicable Disease Dynamics
Feb. 14, 2020

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Hacker leaks passwords for more than 500,000 servers, routers, and IoT devices

A hacker has published this week a massive list of Telnet credentials for more than 515,000 servers, home routers, and IoT (Internet of Things) “smart” devices.

The list, which was published on a popular hacking forum, includes each device’s IP address, along with a username and password for the Telnet service, a remote access protocol that can be used to control devices over the internet.

According to experts to who ZDNet spoke this week, and a statement from the leaker himself, the list was compiled by scanning the entire internet for devices that were exposing their Telnet port. The hacker than tried using (1) factory-set default usernames and passwords, or (2) custom, but easy-to-guess password combinations.

These types of lists — called “bot lists” — are a common component of an IoT botnet operation. Hackers scan the internet to build bot lists, and then use them to connect to the devices and install malware.

These lists are usually kept private, although some have leaked online in the past, such as a list of 33,000 home router Telnet credentials that leaked in August 2017. To our knowledge, this marks the biggest leak of Telnet passwords known to date.

DATA LEAKED BY A DDOS SERVICE OPERATOR

As ZDNet understands, the list was published online by the maintainer of a DDoS-for-hire (DDoS booter) service.

When asked why he published such a massive list of “bots,” the leaker said he upgraded his DDoS service from working on top of IoT botnets to a new model that relies on renting high-output servers from cloud service providers.

www.zdnet.com/article/hacker-leaks-passwords-for-more-than-500000-servers-routers-and-iot-devices/

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How Centralized Banking System Operate And Manage Our Transactions

How centralized banking system looks? Let’s understand this complex traditional banking system by breaking it down layer-by-layer.

Layer 1. Say Bob wants to pay Sasha 10$. Both hold an account with the same bank ‘Deutsche bank’.

Since no money is leaving or entering the bank, they just have to update their accounting system to balance out. So here is how the process will look:
– Bob tells the bank to credit Sasha’s account with 10$.
– Deutsche bank then debits the funds from Bob’s account and credit 10$ to Sasha’s account.

It is done with the Deutsche bank core banking system and They owe now Sasha 10$ more and Bob, 10$ less.

Layer 2. But what if Sasha has a bank account with a different bank, say HSBC. What happens then?

It’s easy for Deutsche Bank to reduce or increase balance in their own system but how to deal with HSBC. If we want HSBC to owe Sasha’s more, they need to owe somebody a little less. So how to persuade HSBC to increase Sasha’s balance by 10$?

The answer to this situation is if Deutsche bank held an account with HSBC and HSBC does the same. Both hold balances with each other and adjust them to make it work out in their respective banking system.

So this is how our challenge in Layer 2 will be solved,
– Deutsche bank reduces 10$ from Bob’s account and adds it to the HSBC account held at their bank.
– Instructs HSBC about the transaction (via SWIFT) that they have increased HSBC balance by 10$ and in turn would like Sasha’s account held at HSBC to be increased by 10$.
– HSBC acknowledging the message debits from Deutsche bank account’s balance and credits Sasha’s with 10$.

Layer 3. The above arrangement works well, but it has problems – Cost and Liquidity.

SWIFT is not cheap: If Deutsche Bank had to send a SWIFT message to HSBC every time Bob pays 10$ to Sasha or other HSBC customers, Bob may face hefty charges for settlement.

Liquidity issue: Think about how much money Deutsche bank would need to have tied up at all its correspondent banks every day. They would need to maintain sizeable balances at all the other banks just in case their customers wanted to send money to a recipient at HSBC or SBI or CITI or wherever. This cash could be invested or lent or otherwise put to other use.

Solution: In theory, all customer transaction from Deutsche bank to HSBC and Vice Versa balances out to very less amount. So what if we kept track of all the payments during the day and only settled the balance?

By adopting this approach, each bank could hold a whole lot less cash at all its corresponding banks. Such an arrangement could cut down the cost and liquidity demands and banks could put their money to work more effectively.

This thinking gave birth to ‘Net settlement systems’. In such an arrangement,
– Messages (or files) are sent to a central “clearing” system, which keeps track of all the payments.
– On the fixed schedule, “clearing system” calculates the net amount owed by each bank to each other.
– Banks then settle amongst themselves by transferring money to/from the accounts they hold with each other.

Layer 4. But this approach also introduces a problem – Delay.

Banks might issue payment instruction in the morning but the receiving bank doesn’t receive the funds until later. The receiving bank, therefore, has to wait until they receive the net settlement, just in case the sending bank goes bust in the interim. This introduces a delay.

To solve this, We need a system like the first one (Bob pays Sasha at the same bank) because it’s really quick. So, If the banks could all hold accounts with a bank that cannot go bust, a bank that sat in the middle of the system ‘central bank’. This thought process motivated the idea of Real-Time Gross Settlement system.

If all banks in a country hold accounts with the central bank, then they can move money between themselves simply by instructing the central bank to debit one account and credit the other. They allow real-time movements of funds between accounts held by banks at their respective central bank.

This final leg works out well but also has limitations.

Remember, settlement in “real-time” means a payment transaction is not subjected to any waiting period. This coordination drives up the cost.

Therefore, settlement in real-time is subject to certain conditions such as payments have to be above a certain threshold. Moreover, all the above-mentioned arrangements are subject to clearing on a certain working hour or day.

Can blockchain replace central banks system

Transferring money in the above traditional systems is time-consuming and requires intermediaries, each of which takes a service charge. Blockchain reduces middlemen while increasing security. Use of blockchain can improve transaction time and save billions.

Many banks have started creating their own blockchain and digital currency such as JP Morgan and Mizuho Financial Group of Japan. At this stage, banks are building a layer 1 solution (remember – Bob wants to pay Sasha 10$. Both hold an account with the same bank) for their customers.
— Citește pe cryptopurview.com/how-centralized-banking-system-manage-our-fund-transaction/